THE EFFECT OF APPLICATION BOVINE AMNIOTIC MEMBRANE ON OSTEOBLASTS, OSTEOCYTES, AND COLLAGEN

Introduction: Tooth extraction can result in loss of alveolar bone. The application biomaterials Bovine Amniotic Membrane (BAM) that containing growth factors and collagen is expected to play a role socket preservation. This study aimed observe the effect BAM on osteoblasts, osteocytes, histological preparate bone Sprague Dawley rats (SD). Methods: 16 male SD were used this group. extracted mandible central incisivus. Afterward, it was divided into two groups, specifically control group (without treatment) treatment (BAM application). After extraction, applied with size 1.5 mm x 10 On 14th 28th day, euthanized mandibular tissue taken stained Hematoxylin Eosin (HE) Masson Trichrome (MT). Results: results all groups showed number osteoblasts thickness higher day compared 28th, while osteocytes continued increase from 28th. collagen, than without application. Statistical there significant differences between (p<0.05). Conclusion: act as material preservation socket. biomaterial accelerate recovery by increasing thickness, osteocytes.